Studying oncogenic signatures in cancers
Cancer is a disease in which abnormal cells acquire the ability to divide without control and invade other tissues. These attributes arise due to genetic and epigenetic alterations that disrupt molecular pathways regulating genomic stability, cell proliferation, and cell death. Since, cancer data analysis involves large numbers of variables, high dimensional clustering methods are required [...]
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Analysis of tumour genomic markers to define pathway deviations
Genomic analysis of cancer will lead to better understanding of cancer biology and help to generate tumour and circulatory molecular markers, that aid early diagnosis and improve the management of the cancer. The main objective of the project is the meta-analysis of published metastatic prostate cancer data sets to generate changes seen to further define [...]
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Studying coevolution of Dengue virus and Host
The number of cases and severity of disease associated with Dengue infection in Sri Lanka has been increasing since 1989. Studies shows that prior to 2009 DENV2 and DENV3 serotypes are dominant and DENV3 caused the epidemics in the years of 2002 and 2004. In 2009 DENV1 was the major disease causing serotype in Sri [...]
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Bioinformatics Workflow development
Next Generation Sequencing (NGS) is a modern technology that generates huge amount of data. Analysis of this data requires computing skills and specialized computing resources. Our objective of this project is to develop easy to use, reproducible workflows for NGS data analysis for the benefit of biologists to carry out their data analysis requirements.
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Human microbiome analysis
Human microbiome is the collective genomes of the microbes (composed of bacteria, bacteriophage, fungi, protozoa and viruses) that live inside and on the human body. Most of the microbes in the microbiome do not cause disease. Humans rely on microbes to perform many important functions that we cannot perform ourselves such as digesting food , [...]
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Vidusayura Ship Handling Simulator
The most effective solution for the ship handling training is the use of a ship simulator. Unfortunately, such simulators are extremely costly. To remedy this situation University of Colombo School of Computing (UCSC) started to develop a ship handling simulator, named ViduSayura. The salient feature of ViduSayura is that is entirely developed using the Commodity [...]
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ICT based home-grown Vessel Traffic Monitoring solution for the Colombo Port
His Excellency the President Mahinda Rajapaksa formally declared open the newly-expanded Colombo South harbor of the Colombo Port including its new Control Tower/Pilot station, Colombo International Container Terminals Ltd (first stage) for business on 5th August 2013. It will allow Sri Lanka to regain its role as a leading South Asia trans-shipment hub. The 56 [...]
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Comprehensive study of Oncogenic signatures
Name of the Researcher(s) Dr. A. R. Weerasinghe Ms. C. R. Wijesinghe Prof. Mahesan Niranjan Ms. S.P.B.M. Senadheera Description Cancer is a major public health issue in Sri Lanka as well as the world over. While extensive cancer research has generated large and valuable data sets, the interpretation of such data remains a major hurdle [...]
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Tamil Digitization Project
Name of the Researcher(s) Dr. AR Weerasinghe - UCSC Mr. Chamila Liyanage - UCSC Dr. Thilini Nadungodage - UCSC Mr. Viraj Welgama - UCSC Dr. EYA Charles - University of Jaffna Dr. S Mahesan - University of Jaffna Dr. A Ramanan - University of Jaffna Description The main goal of this project was to digitize [...]
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Machine Translation System for Sinhala -Tamil Language Pair
Name of the Researcher(s) Dr. A.R. Weerasinghe Randil Pushpananda Thilini Nadungodage Chamila Liyanage Description One of the long standing national issues in Sri Lanka stems from the fact that the two main people groups are conceptually isolated by the language barrier which keeps Sinhala speakers apart from Tamil speakers. While a few attempts using ‘toy’ [...]
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Optical Character Recognition System for Sinhala
Name of the Researcher(s) Dr. A.R. Weerasinghe Mr. Harsha Wijayawardhana Mr. Chamila Liyanage Description Optical Character Recognition (OCR) is a technology that has been widely researched over the past three decades with commercial systems available for English and other languages with Latin-based character sets. The application of OCR to non-Latin character sets has been increasingly [...]
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Speech Recognition System for Sinhala
Name of the Researcher(s) Dr. A.R. Weerasinghe Thilini Nadungodage Randil Pushpananda Chamila Liyanage Description The main goal of this project is to enhance human-computer interaction by developing an Automatic Speech Recognition (ASR) engine that enables users to access computers and other digital devices using the Sinhala language. An ASR system capable of automatically digitizing continuous [...]
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